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Non-invasive Brain Stimulation for People With Stroke

NCT01405378 · University of Southampton · Updated 23 June 2016

What is being tested
Robot therapy and transcranial direct current stimulation
For
Stroke
Kind of study
Tests a treatment or device on volunteers. Early phase 1.
Who can join
Ages 18 years to 80 years. About 23 people. The full rules are on the registry page.
Where
United Kingdom
When
Starts or started Oct 2011, ends Feb 2014. Registered 29 July 2011.
Results
None posted yet.

In the researchers' words

Every five minutes someone in the UK has a stroke. It is the main cause of long-term disability among adults in the UK despite a fall in age-specific stroke incidence, with a growing number of survivors remaining dependent for activities of daily living. While most people with stroke regain walking ability, upper limb problems with no voluntary arm and hand activity, affecting a third of people after stroke, has a poor prognosis. Transcranial direct current stimulation (tDCS) is a non-invasive procedure used to polarise brain regions through the application of weak direct currents and has the potential to develop into a useful aid to treatment strategies in neurorehabilitation. Recent literature into the application of tDCS in people with arm and hand impairments after stroke has shown promising results on upper limb function measures like the Jebsen-Taylor hand function test. Furthermore, a recent pilot study evaluated a six-week training programme combining tDCS with robot-assisted hand training and reported significant improvements in upper limb function. However, the robot in the latter study focused on single-plane distal movements only and long-term effects of the tDCS were not assessed. Recent robotic developments included robots with three rotational degrees-of-freedom for the upper limb, but the effectiveness of this type of robot combined with tDCS in early stroke…
ClinicalTrials.gov, NCT01405378

Sites

  • Faculty of Health Sciences, University of SouthamptonSouthampton, United Kingdom