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The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy

NCT01402622 · Yonsei University · Updated 26 July 2011

What is being tested
Propofol anesthesia
For
Robotic Radical Prostatectomy
Kind of study
Tests a treatment or device on volunteers. Phase 4.
Who can join
Ages 50 years to 70 years. About 93 people. The full rules are on the registry page.
Where
South Korea
When
Starts or started Dec 2010, ends June 2011. Registered 26 July 2011.
Results
None posted yet.

In the researchers' words

To maximize the surgical visual field, Robot-assisted laparoscopic radical prostatectomy (RLRP) usually requires the patient to be positioned in a steep trendelenburg position in combination with prolonged intraperitoneal carbon dioxide (CO2) insufflation and increased intrabdominal pressure. Insufflations of CO2 during laparoscopic surgery, which causes stretch and irritation of the peritoneum, is known to play an important role in postoperative nausea and vomiting (PONV). In addition, prolonged pneumoperitoneum increases the risk for PONV. PONV can cause patient discomfort and prolong post anaesthesia care unit (PACU) stay. In addition, the patient with PONV is also predisposed to severe complications such as aspiration pneumonia, increased wound dehiscence, delayed recovery, prolonged hospital stay, and eventually increased medical cost.
ClinicalTrials.gov, NCT01402622

Sites

  • Severance HospitalSeoul, South Korea