Monday, October 26, 2026 · Daily editionET --:--:--

Finished

Plethysmography Variability Index as an Indicator of Adequacy of Preload

NCT01285622 · University of Louisville · Updated 5 April 2021

What is being tested
Not stated
For
Gynecological Surgery
Kind of study
Watches patients without assigning a treatment. No drug phase (a device or procedure study).
Who can join
Ages 18 years to 65 years. About 77 people. The full rules are on the registry page.
Where
United States
When
Starts or started 1 Jan 2011, ends 28 Nov 2018. Registered 28 Jan 2011.
Results
None posted yet.

In the researchers' words

The investigators propose a prospective observational trial. The investigators plan to enroll 40 female subjects scheduled for elective robotic gynecological surgery under general anesthesia. Hemodynamic data will be recorded at the following intervals: after induction of anesthesia (Baseline), after initiation of pneumoperitoneum, after positioning the patient in Trendelenburg position, and every 15 minutes thereafter. At the end of surgery measurements will be recorded after reversal of Trendelenburg position and after deflation of the peritoneum. Forearm - fingertip temperature gradients will be measured by Mon-a-thermometer (Mallinckrodt Medical, Inc. St. Louis, MO) and disposable Mon-a-therm thermocouples. Vasoconstriction will be identified when forearm - fingertip temperature gradient is ≥ 00C and PI \<1. Intra-abdominal pressures will be recorded during each measurement of hemodynamic parameters. Trendelenburg position will be measured with an angle ruler. The aim of our study is to test the hypothesis that stroke volume will drop significantly after initiation of pneumoperitoneum and that it will increase after placement in Trendelenburg position in patients undergoing robotic gynecological procedures. Secondly, the investigators will test the hypothesis that PVI changes correlate with changes in stroke volume and pulse pressure variation (PPV) and can predict an…
ClinicalTrials.gov, NCT01285622

Sites

  • University of Louisville HospitalLouisville, Kentucky, United States